The 5-Second Trick For Explore https://ligaz.bet/
The 5-Second Trick For Explore https://ligaz.bet/
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in no cost ligase). The surface peptide loop destined to become the latch while in the DNA-certain ligase is disordered during the totally free ligase (
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; with DNA omitted) were being superimposed with regard for their NTase domains after which you can offset laterally to expose the large movement of your OB domain brought on by nick recognition.
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). The NTase domain binds on the damaged and intact DNA strands in the foremost groove flanking the nick in addition to in the minor groove on the three′-OH facet on the nick (supplemental Fig. S3). The OB domain binds across the minor groove on the face of the duplex at the rear of the nick.
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